Tmsb15a (thymosin beta 15a) - Rat Genome Database

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Gene: Tmsb15a (thymosin beta 15a) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Tmsb15a
Name: thymosin beta 15a
RGD ID: 2324583
Description: Predicted to enable actin monomer binding activity and protein sequestering activity. Predicted to be involved in regulation of cell migration. Predicted to be located in cytoskeleton. Predicted to be part of filamentous actin. Orthologous to human TMSB15A (thymosin beta 15A) and TMSB15B (thymosin beta 15B).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100361139; thymosin beta-15A; thymosin-like 8-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X103,463,228 - 103,465,205 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX103,463,228 - 103,465,205 (-)EnsemblGRCr8
mRatBN7.2X98,671,589 - 98,673,566 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX98,671,629 - 98,673,643 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX100,804,799 - 100,806,776 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X104,315,406 - 104,317,383 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
Rnor_6.0X106,213,233 - 106,215,260 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX106,213,279 - 106,214,398 (-)Ensemblrn6Rnor6.0
Rnor_5.0X106,904,921 - 106,906,948 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X123,022,152 - 123,023,274 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX100,469,738 - 100,471,767 (+)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Tmsb15a
2 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X80434318125434318Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX92979612117740458Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
4 3 5 18 34 31 23 6 23 4 61 20 1 9 12 39 8

Sequence


Ensembl Acc Id: ENSRNOT00000078380   ⟹   ENSRNOP00000074123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX103,463,228 - 103,465,205 (-)Ensembl
mRatBN7.2 EnsemblX98,671,629 - 98,673,643 (-)Ensembl
Rnor_6.0 EnsemblX106,213,279 - 106,214,398 (-)Ensembl
RefSeq Acc Id: NM_001401215   ⟹   NP_001388144
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X103,463,228 - 103,465,205 (-)NCBI
mRatBN7.2X98,671,589 - 98,673,566 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001388144 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL85828 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074123
  ENSRNOP00000074123.1
Ensembl Acc Id: ENSRNOP00000074123   ⟸   ENSRNOT00000078380
RefSeq Acc Id: NP_001388144   ⟸   NM_001401215
- UniProtKB: A0A0G2K7A1 (UniProtKB/TrEMBL),   A6KT42 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7A1-F1-model_v2 AlphaFold A0A0G2K7A1 1-45 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2324583 AgrOrtholog
BioCyc Gene G2FUF-1651 BioCyc
Ensembl Genes ENSRNOG00000053780 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078380 ENTREZGENE
  ENSRNOT00000078380.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.520 UniProtKB/TrEMBL
InterPro Beta-thymosin UniProtKB/TrEMBL
  Beta-thymosin_sf UniProtKB/TrEMBL
NCBI Gene 100361139 ENTREZGENE
PANTHER PTHR12021 UniProtKB/TrEMBL
  THYMOSIN BETA 15A UniProtKB/TrEMBL
Pfam Thymosin UniProtKB/TrEMBL
PhenoGen Tmsb15a PhenoGen
PIRSF Thymosin_beta UniProtKB/TrEMBL
RatGTEx ENSRNOG00000053780 RatGTEx
SMART THY UniProtKB/TrEMBL
UniProt A0A0G2K7A1 ENTREZGENE, UniProtKB/TrEMBL
  A6KT42 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-11 Tmsb15a  thymosin beta 15a  LOC100361139  thymosin-like 8-like  Name and Symbol changed 629549 APPROVED
2010-05-06 LOC100361139  thymosin-like 8-like      Symbol and Name status set to provisional 70820 PROVISIONAL