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Gene: WFDC10A (WAP four-disulfide core domain 10A) Chlorocebus sabaeus

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Symbol:

WFDC10A

Name:

WAP four-disulfide core domain 10A

RGD ID:

18573721

Description:

ENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

WAP four-disulfide core domain protein 10A

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	18,213,757 - 18,218,101 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	18,215,355 - 18,216,548 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	66,856,180 - 66,857,801 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

extracellular region (IEA)

Molecular Function

peptidase inhibitor activity (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

WFDC10A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	18,213,757 - 18,218,101 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	18,215,355 - 18,216,548 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	66,856,180 - 66,857,801 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

WFDC10A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	45,629,739 - 45,631,196 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	45,629,739 - 45,631,196 (+)	Ensembl			hg38	GRCh38
GRCh37	20	44,258,378 - 44,259,835 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	43,691,799 - 43,693,245 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	43,691,798 - 43,693,245	NCBI
Celera	20	40,966,905 - 40,968,351 (+)	NCBI		Celera
Cytogenetic Map	20	q13.12	NCBI
HuRef	20	40,999,845 - 41,001,291 (+)	NCBI		HuRef
CHM1_1	20	44,161,110 - 44,162,556 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	47,365,800 - 47,367,257 (+)	NCBI		T2T-CHM13v2.0

Wfdc10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	164,497,966 - 164,499,288 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	164,497,966 - 164,499,288 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	164,656,046 - 164,657,368 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	164,656,046 - 164,657,368 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	164,481,546 - 164,482,868 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	164,347,251 - 164,348,573 (+)	NCBI		MGSCv36	mm8
Celera	2	170,592,405 - 170,593,727 (+)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	85.24	NCBI

Wfdc10a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	173,809,395 - 173,810,748 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	173,809,395 - 173,810,748 (+)	Ensembl				GRCr8
mRatBN7.2	3	153,390,067 - 153,391,420 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	153,390,067 - 153,391,420 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	157,198,452 - 157,199,804 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	165,697,417 - 165,698,769 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	163,441,197 - 163,442,549 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	161,121,690 - 161,123,043 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	161,121,697 - 161,123,069 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	167,298,958 - 167,300,311 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	155,685,441 - 155,686,794 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	151,998,543 - 151,999,896 (+)	NCBI		Celera
Cytogenetic Map	3	q42	NCBI

WFDC10A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	51,368,794 - 51,370,284 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	51,361,903 - 51,363,393 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	41,966,314 - 41,967,804 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	43,055,137 - 43,056,581 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

WFDC10A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	32,909,505 - 32,910,890 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	32,909,505 - 32,910,860 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	32,438,122 - 32,439,508 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	33,618,648 - 33,620,049 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	33,618,648 - 33,620,019 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	32,879,234 - 32,880,620 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	32,995,021 - 32,996,407 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	33,533,443 - 33,534,829 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

LOC100621271
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	47,888,613 - 47,901,430 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	47,899,971 - 47,901,404 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	53,545,955 - 53,547,266 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Wfdc10a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624790	8,832,808 - 8,836,126 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Wfdc10a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	153,302,496 - 153,304,005 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in WFDC10A
113 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
7	4	17	17	17	7	4

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008015864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JBLKOC010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000012553 ⟹ ENSCSAP00000010586

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	2	18,215,355 - 18,216,548 (-)	Ensembl

RefSeq Acc Id:

XM_008015864 ⟹ XP_008014055

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	2	18,213,757 - 18,218,101 (-)	NCBI
Vero_WHO_p1.0	NW_023666050	66,856,180 - 66,857,801 (-)	NCBI

Sequence:

show sequence

GGGCCCAGGCTCCTTTCATCTTTTGGCTTCACTAGGCTCTAGAACCTTGTTTTCATCTATACTG
AGCTGGTGGAAAAGAAAAAGTGTGTGAAAGAGACTTGCCATCTTCTTAGGGTCTTGATCTAGTA
GTGACAAGGCTGTTAGCCGAAATATTTACATTGTGGCACTGGCTGCAAGGTGGTTGGGTAAGGA
AAATGCAGCTTCTGTCTGAAATGATGATTCTCCTCTACATAACCCCTCTTTGCTAGGATAATTA
TGATGGCGTCCAGTCTCTAAATTGTTCATTTATGAGTGGACAAAAAGAAAAACTAGGAAAGAGA
GAGCCTTTGGGAAGGGTCAAACACCACTCTCTAAACTGTAGGTACAAATATCAGAATTTTTGAA
TTATAAAGGATATCGCAAAGGATACAGAGGAAGAGGTACATACGGTGAAATATGGGGAAAGGCT
ATAGAGCTTCCTTTGAATGTAAATTACAACTGTGGACTGAAGGAGACTGCATTAGGAGTTCAGA
ATGTCAGAATGAGGTTCAAATCTTTAGAAGATTATCATCATCAGTGGAAGAGGGTGATCTTCTT
CCCAGCTTCCTTGCCTATTGGGAGTCCAGTGACCCAGGTTGTCCCCTCTCTCTCCTATTAGGGA
AGAAGAAACATCTTCACTTCTGAGAATTCATTTTCTTCATAATATTCAAGGTCAGTGACCACCT
CCTCCTGGACAGCCTGCCAAGCCTTTGACTGATAGGTCTCTCCTCCTGTCTGCGCTCTAAGATA
TTTACTATGTTTCCCCATTAGCCCTTCTGTCCCATGCCCTACAATAGTCTCTCTTTCTGTATGT
ATATGTGTATTTAAATTTGTATATGTGTATGTGTGTATGTGTTTATATATGTTTACATATGAAA
CAGATACTTACTCTTTCACTCAGGAATTCTAACTCTCTTAGTCTAAAGAAATAAAAGATTTATA
AATAAAGATGTTCAATATGACATTCTTTAGATTATTAGTAATTAGTACAATACAAATACTTGAT
TATTAGCATTTAAGTGAGAGCTGTGCAATTATGAAAATCCACATTTTGAGAAATACTTACATGA
TTAAATAAGGGTGGCAAAAATAGGTAACAAAAGATGTTTGTATTAAAAGGATTGTTTATATTAA
ATATGGAGAGCAACTAAAAGATAATGCAATGAAACATCAGTTAATTCTAAGCAACTCTTTCTAA
AAATATATTTTTTCTTTTCTTTTTTCCATAAAACATTTTGTAGTTAGGAAGCAGAAATAAATGA
TATCTTTCATTCTACCAGCAAGAACACAACTGGTAATGTGAGAGGAGGAGGCGTCATTCCTGCG
GAAGCCCTATCCCACGTGAAGAAGGACAGGATTAGGGGCAAAGAAAAGGAGGAAGCCAAGACTC
TCTTGCTCTGCCCCGACTCGGCCAGTGGAGGCAGTGAGAAGCTGAAGATCATTCCTTCTTTCTT
TCCTTCACTCTCCACAGGCAGCTCTGCAGGGAAGTCTGTGACTGCCTGGTCAGACTTAGGGCCC
ACGCTGTGGTCAGAGTCATGCCATCCCAGACTCTGCTGCCTGTCCTGGTTCTCTGTGTGTTGCT
GCTTCAGGCCCAGGGAGGATACCGTGACAAGAAGAGGATGCAGAAAACACAGCTATCCCCAGAA
ATTAAAGTCTGCCAGCAACAGCCTAAACTATATCTATGCAAACGCTCCTGTGAATCTCACCGAG
ACTGTCAAGCAAATAACATATGCTGTTCTACCTACTGTGGGAATGTTTGCATGAGCATCCTGTG
AGTGGGAGACTGGGCTGGGATGTGTATCCTGCTTCCCAACTCCTCTATCCAAGACTGTGCCCAC
ATCCGAAGCACAAGGACTTCAAGTCACCAGCATAAGAACATCAACAGGAATGCCGCCCTCCCTA
CTGTCTGAACTCCTTGTCCCTGCCAAATAAACCAGAACAAATGTTCAGGGATCCTGCCTCTTTC
GCTGCCACTACAGGTGATCATTGAGAGCCCACTGTAGCCCCCACTCGTCTTGTGTCCTGGTGTT
CGATTTCTCTCCCTGGCTATGCTTCTCTACCCTCCCTCTCCCTCTTTGGCCCATATATCCCTGC
CAGCCCTCAGGAGGCCCAGCCCCTTGCTGTTTTGCTGACTGAACCAGTACTCCCAGGGGGAGGA
ACTGCTCATGTGCAGCATCTCCCGATGCTAAGGAGAACATTTCTCACCCTGGAGTCAGAAGGAC
CCATTAAGCATGAGATGGGTGGCAGTTAGAACCCGAGGTAAAGAGTGGGAGACCCCCAAGCACT
GCTTTGGTCTCCTTAGCCTTGGTGCACCCCCATCCCATGCTCCCCAATCTCTCTGTAAGGTTCA
CATTACTGTCTATTTATCATTAGGATAATGAGTCCCAGAAGCCCAGCAAGACCAAGGCCACAAG
AGAGTGAGAGGATATGATGTGGCCAGAAGAGGGTGTTTCTTCTAGGCTGACTTTTTCCTCACTT
CTCTCCATTACCTGAGACCAGAGGCATCCTAGTGAGAGTGAGTGCCTGCACCAACCCCAAAGCT
CCTCCCATCCAGCACCCACCAATATGGCTACTCCTCTGATGGGACCCATTTTAGGCCTCAGGAT
CTGACACTCCAGTACCTTCCATTAACTGAATAGTCCCTATCCTTCCCAAGCCCTCTTCCTTAGG
GGCCAGTTTATTCTCTTTTCTTTAGATCAAGAGGAACACTAAGGGATGTGGAACAGGTGGTTCA
TGCTGCTGTTGCTAAGGAGTAATTGGCACAGAGTGGCTACGGGTCTTCCCTGTCATCCTGCTGT
GAGTTAGTGGAAATTAATCAGTGTGGTACAGAATCTCCTTCTCTGTGCAATTGCAACTCCTCTG
AAATGATCCTGGGGTTAGATCCAGGGTTGGGTCACATGTAGCTAACTGGGACATGAAGCCAAAA
GTGAAGAGGTTTCAGGAGGACAGGCCATGCCCAGAGGCAGGTGTGCAGTGTTATGCTCCAGTCT
AGTGCTTCTTGCTGGGCCATTCAATGAAATAGACATCAGAGAAGAAAACTTCCCCCATCAGACC
AGAGGCTGTGAGTCACCTCTGAGTCATCACCAGGCTTTGGGTATCTCAGGTTTGTTTTCACCTT
TCTCAAGAGCTTCCCTTGGACAAGGACGTCTTAGGAAAGAGATCATCATCAACCACCAACAGAC
ATCAAATGTAGTCGGTGGGCTGTAAGAGCATGATCTCCAAGAGACCTTATTTGGTATTTCCTCG
GATAGCCTCCCTTACCAAGCATCCTCTCAAGCCATCTCCAAACACACCTCCTAGACACTACAGG
CATGTCTGCTTTTATTGAGCCTTGCTCTATTGCACTTCACAGCTATAGTGTTTCATACAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008014055	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000010586
	ENSCSAP00000010586.1

RefSeq Acc Id:	XP_008014055 ⟸ XM_008015864
- UniProtKB:	A0A0D9RPP7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000010586 ⟸ ENSCSAT00000012553

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000014461	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000012553.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.75.10	UniProtKB/TrEMBL
InterPro	Elafin-like_sf	UniProtKB/TrEMBL
	WAP_dom	UniProtKB/TrEMBL
KEGG Report	csab:103245323	UniProtKB/TrEMBL
NCBI Gene	WFDC10A	ENTREZGENE
Pfam	WAP	UniProtKB/TrEMBL
PROSITE	WAP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57256	UniProtKB/TrEMBL
UniProt	A0A0D9RPP7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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