ENCODES a protein that exhibits cysteine-type endopeptidase activator activity (inferred); DNA binding (inferred); double-stranded DNA binding (inferred); INVOLVED IN cellular response to interferon-beta (ortholog); cellular response to xenobiotic stimulus (ortholog); positive regulation of interleu
kin-1 beta production (ortholog); PARTICIPATES IN interleukin-1 signaling pathway; ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); multiple sclerosis (ortholog); FOUND IN cytoplasm (ortholog)
ENCODES a protein that exhibits CARD domain binding (inferred); caspase binding (inferred); cysteine-type endopeptidase activity (inferred); INVOLVED IN cellular response to lipopolysaccharide (inferred); negative regulation of interleukin-1 beta production (inferred); negative regulation of lipopol
ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); negative regulation of interleukin-1 beta production (ortholog); FOUND IN AIM2 inflammasome complex (inferred); IPAF inflammasom
ENCODES a protein that exhibits cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); INVOLVED IN proteolysis (inferred); regulation of apoptotic process (inferred); regulation of inflammatory response (inferred); FOUND IN AIM2