Enables alpha-(1->3)-fucosyltransferase activity. Involved in N-glycan fucosylation and neuronal stem cell division. Acts upstream of or within cerebral cortex radially oriented cell migration; neuroblast migration; and neuronal stem cell population maintenance. Predicted to be located in Golgi appa
ratus; endoplasmic reticulum; and nucleoplasm. Predicted to be active in endoplasmic reticulum membrane. Is expressed in central nervous system and retina. Orthologous to human FUT10 (fucosyltransferase 10). [provided by Alliance of Genome Resources, Apr 2025]
This gene is one of three genes in mouse which encode a galactoside 2-L-fucosyltransferase. These genes differ in their developmental- and tissue-specific expression. This gene is predicted to encode a type II membrane protein, which is anchored in the Golgi apparatus and controls the final step in
the creation of alpha (1,2) fucosylated carbhohydrates by the addition of a terminal fucose in an alpha (1,2) linkage. The biological function of the fucosylated carbhohydrate products is thought to involve cell-adhesion and interactions with microorganisms. [provided by RefSeq, Dec 2012]