Wdr45 Gene Search Result

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2 records found for search term Wdr45

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1550935	Wdr45	WD repeat domain 45	Predicted to enable phosphatidylinositol phosphate binding activity; protein kinase binding activity; and protein-macromolecule adaptor activity. Predicted to be involved in several processes, including autophagy of mitochondrion; macroautophagy; and positive regulation of autophagosome assembly. Pr ... (more) edicted to be located in phagophore assembly site. Predicted to be active in cytosol and phagophore assembly site membrane. Is expressed in several structures, including adrenal gland; brain; early embryo; genitourinary system; and pancreas. Used to study neurodegeneration with brain iron accumulation 5. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation 5. Orthologous to human WDR45 (WD repeat domain 45). [provided by Alliance of Genome Resources, Jul 2025]	X	7588212	7594439	Mouse	189	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1553369	Wdr45b	WD repeat domain 45B	Predicted to enable TSC1-TSC2 complex binding activity; phosphatidylinositol phosphate binding activity; and protein-macromolecule adaptor activity. Predicted to be involved in autophagy of mitochondrion; cellular response to starvation; and macroautophagy. Predicted to be located in lysosome and ph ... (more) agophore assembly site. Predicted to be active in cytosol and phagophore assembly site membrane. Orthologous to human WDR45B (WD repeat domain 45B). [provided by Alliance of Genome Resources, Jul 2025]	11	121218029	121246393	Mouse	107	symbol , old_gene_name , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]