Predicted to enable histone binding activity and peptidase activity. Predicted to be involved in mRNA splicing, via spliceosome and negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is e
xpressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human USP49 (ubiquitin specific peptidase 49). [provided by Alliance of Genome Resources, Apr 2025]
This locus represents naturally-occurring readthrough transcription between the neighboring mediator complex subunit 20 (Med20) and ubiquitin specific peptidase 49 (Usp49) genes. Readthrough transcripts may be candidates for nonsense mediated decay (NMD) or enco