Usf2 Gene Search Result

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3 records found for search term Usf2

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
734371	Usf2	upstream transcription factor 2	Enables DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in glucose mediated signaling pathway; lipid homeostasis; and positive regulation of transcription from RNA polymerase II promoter by glucose. Acts upstream of or within lactation; pos ... (more) itive regulation of DNA-templated transcription; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and sensory organ. Orthologous to human USF2 (upstream transcription factor 2, c-fos interacting). [provided by Alliance of Genome Resources, Jul 2025]	7	30645421	30656288	Mouse	150	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1623022	Usf2-ps1	upstream transcription factor 2, pseudogene 1		7	30625358	30626571	Mouse		symbol , PhenoGen	gene, pseudo, INFERRED [RefSeq]
1551792	Usf1	upstream transcription factor 1	This protein encoded by this gene is a member of the basic-Helix-Hoop-Helix-Leucine zipper (bHLH-LZ) family and encodes a protein that can act as a transcription factor. Studies indicate that the basic region interacts with DNA at E-Box motifs, while the helix-loop-helix and leucine zipper domains a ... (more) re involved in dimerization with different partners. This protein is involved in a wide array of biological pathways, including cell cycle regulation, immune response, and responses to ultraviolet radiation. Mice lacking most of the coding exons of this gene often lacked both whiskers and nasal fur, and were prone to epileptic seizures, while mice lacking both this gene and another family member, Usf2, displayed embryonic lethality (PMID:9520440). Mutations in the human ortholog of this gene have been associated with Familial Combined Hyperlipidemia (FCHL) in humans. Pseudogenes of this gene are found on chromosome 11 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]	1	171238881	171246327	Mouse	165	description	gene, protein-coding, REVIEWED [RefSeq]