| 1318757 | Tnks | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | Predicted to enable histone binding activity; pentosyltransferase activity; and zinc ion binding activity. Predicted to be involved in several processes, including positive regulation of canonical Wnt signaling pathway; post-translational protein modification; and regulation of chromosome organizati on. Predicted to act upstream of or within peptidyl-serine phosphorylation and peptidyl-threonine phosphorylation. Located in cytosol. Is expressed in several structures, including blastocyst; central nervous system; early embryo; neural retina; and oocyte. Orthologous to human TNKS (tankyrase). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 35296333 | 35432844 | Mouse | 217 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1552096 | Tnks2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | Predicted to enable NAD+ poly-ADP-ribosyltransferase activity; NAD+-protein mono-ADP-ribosyltransferase activity; and enzyme binding activity. Acts upstream of or within regulation of growth. Predicted to be located in nuclear envelope; pericentriolar material; and perinuclear region of cytoplasm. P redicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; early embryo; eye; and genitourinary system. Orthologous to human TNKS2 (tankyrase 2). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 36811583 | 36870877 | Mouse | 147 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1323787 | Tnks1bp1 | tankyrase 1 binding protein 1 | Predicted to enable ankyrin repeat binding activity and enzyme binding activity. Predicted to be involved in cellular response to ionizing radiation; double-strand break repair; and positive regulation of protein phosphorylation. Predicted to be located in adherens junction; cytoplasm; and plasma me mbrane. Predicted to be part of CCR4-NOT complex. Predicted to be active in heterochromatin and nucleus. Orthologous to human TNKS1BP1 (tankyrase 1 binding protein 1). [provided by Alliance of Genome Resources, Apr 2025] | 2 | 84878356 | 84903392 | Mouse | 148 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |