Tal1 Gene Search Result

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2 records found for search term Tal1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1315544	Tal1	T cell acute lymphocytic leukemia 1	Enables DNA-binding transcription factor activity, RNA polymerase II-specific; E-box binding activity; and chromatin binding activity. Contributes to DNA binding activity. Involved in embryonic hemopoiesis; positive regulation of erythrocyte differentiation; and regulation of transcription by RNA po ... (more) lymerase II. Acts upstream of with a positive effect on transcription by RNA polymerase II. Acts upstream of or within several processes, including hemopoiesis; neurogenesis; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; embryo mesenchyme; extraembryonic component; hemolymphoid system; and sensory organ. Used to study lymphoid leukemia. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Orthologous to human TAL1 (TAL bHLH transcription factor 1, erythroid differentiation factor). [provided by Alliance of Genome Resources, Jul 2025]	4	114913623	114928952	Mouse	268	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1312721	Stil	Scl/Tal1 interrupting locus	This gene encodes a centrosomal protein ubiquitously expressed in proliferating cells and during early embryonic development. Mice lacking the encoded protein die in utero with marked growth retardation, defects in the developing neural fold and randomization of left-right asymmetry. Alternative spl ... (more) icing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]	4	114857287	114900404	Mouse	154	old_gene_name , name	gene, protein-coding, REVIEWED [RefSeq]