serine/threonine kinase receptor associated protein
Enables U2 snRNP binding activity; mRNA binding activity; and signaling receptor binding activity. Involved in alternative mRNA splicing, via spliceosome; neuron differentiation; and protein-RNA complex assembly. Acts upstream of or within negative regulation of transcription by RNA polymerase II; n
egative regulation of transforming growth factor beta receptor signaling pathway; and retinoic acid catabolic process. Is active in nucleus. Is expressed in several structures, including alimentary system; branchial arch; metanephros; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in adenocarcinoma; colorectal carcinoma; large cell carcinoma; lung carcinoma; and squamous cell neoplasm. Orthologous to human STRAP (serine/threonine kinase receptor associated protein). [provided by Alliance of Genome Resources, Jul 2025]
Predicted to be involved in maturation of SSU-rRNA. Located in nucleus. Is expressed in several structures, including axial musculature; genitourinary system; neural ectoderm; orbito-sphenoid; and submandibular gland primordium. Orthologous to human SRFBP1 (serum response factor binding protein 1).