Enables SUMO-specific endopeptidase activity and deSUMOylase activity. Involved in protein desumoylation and protein sumoylation. Acts upstream of or within negative regulation of proteasomal ubiquitin-dependent protein catabolic process and regulation of definitive erythrocyte differentiation. Is a
ctive in postsynaptic cytosol and presynaptic cytosol. Is expressed in embryo and heart. Used to study type 1 diabetes mellitus. Orthologous to human SENP1 (SUMO specific peptidase 1). [provided by Alliance of Genome Resources, Jul 2025]
Predicted to enable deSUMOylase activity. Predicted to be involved in protein desumoylation. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]