Predicted to enable transcription corepressor activity. Predicted to be involved in positive regulation of apoptotic process and regulation of RNA metabolic process. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in cytosol and nuclear speck
. Predicted to be part of ASAP complex; nucleus; and transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; limb; and sensory organ. Orthologous to human SAP18 (Sin3A associated protein 18). [provided by Alliance of Genome Resources, Jul 2025]
14
58035646
58042437
Mouse
128
symbol , old_gene_name , PhenoGen , description , old_gene_symbol
This intronless gene is highly similar to the multi-exon Sap18 gene on chromosome 14, whose product functions in transcriptional repression as a component of the Sin3 histone deacetylase complex. This gene may possibly be a Sap18
span> pseudogene, but it is represented as protein-coding because it appears to be transcribed and has an intact ORF that would result in a protein that is 100% identical to the Sap18 protein. [provided by RefSeq, Dec 2008]
Predicted to enable transcription cis-regulatory region binding activity. Acts upstream of or within establishment of Sertoli cell barrier; regulation of gene expression; and spermatogenesis. Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Predicted to be part of Sin3-type comple
x. Predicted to be active in nucleus. Is expressed in testis. Orthologous to human ARID4B (AT-rich interaction domain 4B). [provided by Alliance of Genome Resources, Jul 2025]