Predicted to enable RNA endonuclease activity. Predicted to be involved in RNA catabolic process. Predicted to be located in endoplasmic reticulum lumen; extracellular space; and lysosome. Predicted to be active in extracellular region. Is expressed in several structures, including alimentary system
; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including Lynch syndrome; RNASET2-deficient cystic leukoencephalopathy; colorectal cancer (multiple); lung cancer; and mismatch repair cancer syndrome. Orthologous to human RNASET2 (ribonuclease T2). [provided by Alliance of Genome Resources, Jul 2025]
17
8347412
8367078
Mouse
132
symbol , ensembl_gene_symbol , PhenoGen , description , old_gene_symbol
Predicted to enable RNA endonuclease activity. Predicted to be involved in RNA catabolic process. Predicted to be located in endoplasmic reticulum lumen; extracellular space; and lysosome. Predicted to be active in extracellular region. Is expressed in several structures, including alimentary system
; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including Lynch syndrome; RNASET2-deficient cystic leukoencephalopathy; colorectal cancer (multiple); lung cancer; and mismatch repair cancer syndrome. Orthologous to human RNASET2 (ribonuclease T2). [provided by Alliance of Genome Resources, Jul 2025]