Enables GTPase activating protein binding activity and GTPase activator activity. Involved in several processes, including learning or memory; negative regulation of signal transduction; and regulation of synaptic plasticity. Acts upstream of or within mitotic cell cycle. Located in several cellular
components, including dendritic spine; microtubule cytoskeleton; and nuclear body. Is active in glutamatergic synapse and postsynaptic density. Is expressed in several structures, including cochlea; neural ectoderm; and placenta. Human ortholog(s) of this gene implicated in nephrolithiasis. Orthologous to human RGS14 (regulator of G protein signaling 14). [provided by Alliance of Genome Resources, Jul 2025]
Enables GTPase activator activity. Involved in G protein-coupled receptor signaling pathway and positive regulation of GTPase activity. Located in membrane. Is expressed in several structures, including central nervous system; limb mesenchyme; lip; neural retina; and skeletal musculature. Orthologou