Enables all-trans-retinol dehydrogenase (NAD+) activity. Acts upstream of or within retinol metabolic process and visual perception. Predicted to be active in cytosol. Is expressed in eye. Used to study age related macular degeneration 2. Orthologous to human RDH8
Enables steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in brexanolone catabolic process and retinol metabolic process. Predicted to be located in early endosome membrane and endoplasmic reticulum. Predicted to be active in intra
cellular membrane-bounded organelle. Orthologous to human HSD17B6 (hydroxysteroid 17-beta dehydrogenase 6). [provided by Alliance of Genome Resources, Apr 2025]