Predicted to enable p53 binding activity. Predicted to be involved in intrinsic apoptotic signaling pathway by p53 class mediator. Predicted to be located in several cellular components, including cytosol; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be active in nucleus. Is expres
sed in several structures, including blood; brain; cardiovascular system; embryo mesenchyme; and yolk sac. Orthologous to human PPP1R13B (protein phosphatase 1 regulatory subunit 13B). [provided by Alliance of Genome Resources, Jul 2025]
Predicted to enable identical protein binding activity. Involved in negative regulation of inflammatory response. Acts upstream of or within several processes, including cardiac muscle contraction; heart development; and negative regulation of transcription by RNA polymerase II. Predicted to be loca
ted in cell junction; cytosol; and intercellular bridge. Is expressed in esophagus; sensory organ; submandibular gland primordium; and vibrissa. Used to study arrhythmogenic right ventricular cardiomyopathy. Orthologous to human PPP1R13L (protein phosphatase 1 regulatory subunit 13 like). [provided by Alliance of Genome Resources, Apr 2025]