Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within nucleocytoplasmic transport. Located in cytoplasm and nucleus. Is expressed in several
structures, including central nervous system; craniocervical region bone; rib; testis; and urinary system. Orthologous to human MLXIP (MLX interacting protein). [provided by Alliance of Genome Resources, Jul 2025]
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Contributes to DNA binding activity. Involved in glucose me
diated signaling pathway; positive regulation of insulin secretion involved in cellular response to glucose stimulus; and regulation of primary metabolic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is active in nucleoplasm. Is expressed in several structures, including central nervous system; gut; liver; metanephros; and nose. Used to study irritable bowel syndrome. Human ortholog(s) of this gene implicated in coronary artery disease and myocardial infarction. Orthologous to human MLXIPL (MLX interacting protein like). [provided by Alliance of Genome Resources, Jul 2025]