| 1321028 | Mettl2 | methyltransferase 2, methylcytidine | Enables tRNA (cytidine-3-)-methyltransferase activity. Involved in tRNA methylation. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; heart; respiratory system; and sensory organ. Orthologous to several human genes includi ng METTL2A (methyltransferase 2A, tRNA N3-cytidine). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 105017251 | 105031972 | Mouse | 60 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1552244 | Etfbkmt | electron transfer flavoprotein beta subunit lysine methyltransferase | Enables protein-lysine N-methyltransferase activity. Involved in negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase and peptidyl-lysine trimethylation. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in mitoc hondrial matrix. Is expressed in several structures, including central nervous system; gut; male reproductive gland or organ; respiratory system; and thymus. Orthologous to human ETFBKMT (electron transfer flavoprotein subunit beta lysine methyltransferase). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 149042980 | 149052669 | Mouse | 98 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1332327 | Mettl22 | methyltransferase 22, Kin17 lysine | Predicted to enable heat shock protein binding activity and protein methyltransferase activity. Predicted to be involved in protein methylation. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Is expressed i n several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeleton. Orthologous to human METTL22 (methyltransferase 22, Kin17 lysine). [provided by Alliance of Genome Resources, Apr 2025] | 16 | 8288623 | 8308069 | Mouse | 79 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1314817 | Mettl23 | methyltransferase like 23 | Enables histone H3R17 methyltransferase activity. Involved in epigenetic programming in the zygotic pronuclei. Acts upstream of with a positive effect on epigenetic programing of male pronucleus. Located in cytoplasm and female pronucleus. Is active in male pronucleus. Is expressed in embryo. Used t o study glaucoma. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 44. Orthologous to human METTL23 (methyltransferase 23, arginine). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 116734341 | 116740566 | Mouse | 122 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1622847 | Mettl24 | methyltransferase like 24 | Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in extracellular region. Orthologous to human METTL24 (methyltransferase like 24). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 40558447 | 40687080 | Mouse | 36 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1321072 | Mettl25 | methyltransferase like 25 | Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Is expressed in adrenal gland; ganglia; telencephalon; and testis. Orthologous to human METTL25 (methyltransferase like 25). [provided by Alliance of Genome Resources, Jul 2 025] | 10 | 105599052 | 105677246 | Mouse | 34 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1316179 | Mettl26 | methyltransferase like 26 | Is expressed in cerebral cortex ventricular layer; cortical plate; embryo; and pancreas epithelium. Orthologous to human METTL26 (methyltransferase like 26). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 26094474 | 26096137 | Mouse | 48 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1551225 | Mettl27 | methyltransferase like 27 | Orthologous to human METTL27 (methyltransferase like 27). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 134961158 | 134971491 | Mouse | 61 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1323482 | Mettl21a | methyltransferase 21A, HSPA lysine | Predicted to enable ATPase binding activity; Hsp70 protein binding activity; and protein-lysine N-methyltransferase activity. Predicted to be involved in peptidyl-lysine methylation. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in c ytosol. Orthologous to human METTL21A (methyltransferase 21A, HSPA lysine). [provided by Alliance of Genome Resources, Apr 2025] | 1 | 64645632 | 64661926 | Mouse | 82 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1621157 | Mettl21c | methyltransferase 21C, AARS1 lysine | Enables protein-lysine N-methyltransferase activity. Involved in protein methylation. Acts upstream of or within several processes, including cellular response to dexamethasone stimulus; hormone-mediated apoptotic signaling pathway; and regulation of release of sequestered calcium ion into cytosol b y sarcoplasmic reticulum. Predicted to be located in cytoplasm and nucleus. Predicted to be part of protein-containing complex. Is expressed in alimentary system; diaphragm; genitourinary system; skeletal muscle; and skin. Orthologous to human METTL21C (methyltransferase 21C, AARS1 lysine). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 44048559 | 44081745 | Mouse | 51 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1622771 | Mettl21e | methyltransferase like 21E | Predicted to enable protein methyltransferase activity. Predicted to be involved in methylation. Is expressed in embryo. Orthologous to human METTL21EP (methyltransferase like 21E, pseudogene). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 44238651 | 44258260 | Mouse | 17 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1322629 | Mettl25b | methyltransferase like 25B | Predicted to be located in membrane. Orthologous to human METTL25B (methyltransferase like 25B). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 87829908 | 87838337 | Mouse | 36 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1620342 | Eef1akmt3 | EEF1A lysine methyltransferase 3 | Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Predicted to be located in several cellular components, including centrosome; chromosome; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosol. Orthologous to human EEF1AKMT3 (EEF1A lysine methyltransferase 3). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 126868654 | 126877883 | Mouse | 70 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1614212 | Vcpkmt | valosin containing protein lysine (K) methyltransferase | Enables protein methyltransferase activity. Involved in peptidyl-lysine trimethylation. Located in cytoplasm. Orthologous to human VCPKMT (valosin containing protein lysine methyltransferase). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 69623504 | 69629883 | Mouse | 80 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |