Mbd3 Gene Search Result

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3 records found for search term Mbd3

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1316563	Mbd3	methyl-CpG binding domain protein 3	This gene encodes a member of the MBD family of nuclear proteins that contain a methyl-CpG binding domain (MBD). The encoded protein is a component of the nucleosome remodeling and histone deacetylation (NuRD) complex. Deletion of this gene causes embryonic lethality in mice. Embryonic stem cells la ... (more) cking the encoded protein are severely compromised in their ability to differentiate and fail to commit to developmental lineages in the absence of leukemia inhibitory factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]	10	80228373	80235365	Mouse	150	symbol , old_gene_name , PhenoGen	gene, protein-coding, REVIEWED [RefSeq]
1317931	Mbd3l1	methyl-CpG binding domain protein 3-like 1	Predicted to enable methyl-CpG binding activity. Predicted to be involved in DNA methylation-dependent constitutive heterochromatin formation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MBD3 ... (more) an>L1 (methyl-CpG binding domain protein 3 like 1). [provided by Alliance of Genome Resources, Jul 2025]	9	18389655	18396594	Mouse	22	symbol , old_gene_name , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1318832	Mbd3l2	methyl-CpG binding domain protein 3-like 2	Predicted to enable methyl-CpG binding activity. Predicted to be involved in DNA methylation-dependent constitutive heterochromatin formation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including MBD3 ... (more) nt-weight:700;'>MBD3L2 (methyl-CpG binding domain protein 3 like 2). [provided by Alliance of Genome Resources, Jul 2025]	9	18341911	18357612	Mouse	29	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]