Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be active in keratin filament. Is expressed in digit epidermis and hair shaft. Human ortholog(s) of this gene implicated in hair disease and mon
Predicted to enable carbohydrate binding activity and protein heterodimerization activity. Predicted to be a structural constituent of skin epidermis. Acts upstream of or within establishment of skin barrier and negative regulation of inflammatory response. Located in keratin filament. Is active in
cornified envelope. Is expressed in autopod; nose; skin; and tongue. Used to study epidermolytic hyperkeratosis. Human ortholog(s) of this gene implicated in KRT1-related nonepidermolytic palmoplantar keratoderma; epidermolytic hyperkeratosis; epidermolytic hyperkeratosis 1; epidermolytic palmoplantar keratoderma 2; and keratosis palmoplantaris striata 3. Orthologous to human KRT1 (keratin 1). [provided by Alliance of Genome Resources, Jul 2025]
Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be active in keratin filament. Human ortholog(s) of this gene implicated in breast cancer; erythrokeratodermia variabilis et progressiva 5; hair
disease; and monilethrix. Orthologous to several human genes including KRT81 (keratin 81); KRT83 (keratin 83); and KRT86 (keratin 86). [provided by Alliance of Genome Resources, Apr 2025]