Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity. Involved in several processes, including canonical Wnt signaling pathway;
establishment of skin barrier; and fat cell differentiation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; regulation of DNA-templated transcription; and regulation of blastocyst development. Located in cytoplasm; euchromatin; and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; limb; and skin. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human KLF4 (KLF transcription factor 4). [provided by Alliance of Genome Resources, Jul 2025]
Located in sarcoplasm. Is expressed in several structures, including blood vessel wall; central nervous system; embryo mesenchyme; male reproductive gland or organ; and musculature. Orthologous to human BAALC (BAALC binder of MAP3K1 and KLF4). [provided by Allia