Enables G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential and G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential. Acts upstream of or within regulation of G protein-coupled recepto
r signaling pathway. Part of receptor complex. Is active in GABA-ergic synapse; postsynaptic membrane; and presynaptic active zone membrane. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and inner ear. Orthologous to human KCTD12 (potassium channel tetramerization domain containing 12). [provided by Alliance of Genome Resources, Jul 2025]
Enables G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential. Acts upstream of or within regulation of G protein-coupled receptor signaling pathway. Part of receptor complex. Is active in GABA-ergic synapse and presynaptic active zone membrane