| 736363 | Kcnj1 | potassium inwardly-rectifying channel, subfamily J, member 1 | Predicted to enable several functions, including ATP-activated inward rectifier potassium channel activity; anion binding activity; and potassium ion binding activity. Acts upstream of or within several processes, including regulation of G-protein activated inward rectifier potassium channel activit y; renal sodium ion absorption; and tissue homeostasis. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is expressed in heart and metanephros. Used to study Bartter disease type 2. Human ortholog(s) of this gene implicated in Bartter disease type 2. Orthologous to human KCNJ1 (potassium inwardly rectifying channel subfamily J member 1). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 32283714 | 32310493 | Mouse | 138 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 736667 | Kcnj3 | potassium inwardly-rectifying channel, subfamily J, member 3 | Contributes to G-protein activated inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and regulation of monoatomic ion transmembrane transport. Part of inward rectifier potassium channel complex. Is active in parallel fiber to Purkinj e cell synapse and presynaptic membrane. Is expressed in several structures, including adrenal gland; alimentary system; brain; male reproductive gland or organ; and thymus. Orthologous to human KCNJ3 (potassium inwardly rectifying channel subfamily J member 3). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 55301814 | 55488157 | Mouse | 193 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 62113 | Kcnj10 | potassium inwardly-rectifying channel, subfamily J, member 10 | Enables inward rectifier potassium channel activity. Involved in cellular response to potassium ion and non-motile cilium assembly. Acts upstream of or within several processes, including adult walking behavior; glutamate reuptake; and regulation of resting membrane potential. Located in astrocyte p rojection; basolateral plasma membrane; and cell body. Is active in ciliary base. Is expressed in several structures, including brain; cochlea; genitourinary system; spinal cord; and stomach. Used to study EAST syndrome. Human ortholog(s) of this gene implicated in EAST syndrome and autosomal recessive nonsyndromic deafness 4. Orthologous to human KCNJ10 (potassium inwardly rectifying channel subfamily J member 10). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 172168777 | 172201652 | Mouse | 289 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 69099 | Kcnj11 | potassium inwardly rectifying channel, subfamily J, member 11 | Enables ATP binding activity; ATP-activated inward rectifier potassium channel activity; and ankyrin binding activity. Involved in negative regulation of insulin secretion and potassium ion import across plasma membrane. Acts upstream of or within several processes, including CAMKK-AMPK signaling ca scade; determination of adult lifespan; and response to ischemia. Located in T-tubule. Part of inward rectifying potassium channel. Is active in cytoplasm and plasma membrane. Is expressed in several structures, including brain; cardiovascular system; gut; skeletal muscle tissue; and testis. Used to study permanent neonatal diabetes mellitus. Human ortholog(s) of this gene implicated in glucose metabolism disease (multiple). Orthologous to human KCNJ11 (potassium inwardly rectifying channel subfamily J member 11). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 45746545 | 45750215 | Mouse | 424 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 733299 | Kcnj12 | potassium inwardly-rectifying channel, subfamily J, member 12 | Predicted to enable PDZ domain binding activity and inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane; protein homotetramerization; and regulation of monoatomic ion transmembrane transport. Predicted to be located in T-tubule; dendri te; and neuronal cell body. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and integumental system. Orthologous to several human genes including KCNJ12 (potassium inwardly rectifying channel subfamily J member 12). [provided by Alliance of Genome Resources, Apr 2025] | 11 | 60912970 | 60964095 | Mouse | 148 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 2299525 | Kcnj13 | potassium inwardly-rectifying channel, subfamily J, member 13 | Predicted to enable inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and regulation of monoatomic ion transmembrane transport. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is exp ressed in brain; male reproductive gland or organ; metanephros; and respiratory system. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 16 and snowflake vitreoretinal degeneration. Orthologous to human KCNJ13 (potassium inwardly rectifying channel subfamily J member 13). [provided by Alliance of Genome Resources, Apr 2025] | 1 | 87312299 | 87322451 | Mouse | 111 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 735433 | Kcnj14 | potassium inwardly-rectifying channel, subfamily J, member 14 | Predicted to enable inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and regulation of monoatomic ion transmembrane transport. Predicted to be located in dendrite and neuronal cell body. Predicted to be part of monoatomic ion channe l complex. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; jaw; limb; nervous system; and oral epithelium. Orthologous to human KCNJ14 (potassium inwardly rectifying channel subfamily J member 14). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 45465871 | 45474180 | Mouse | 63 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 731051 | Kcnj15 | potassium inwardly-rectifying channel, subfamily J, member 15 | Enables potassium channel activity. Acts upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; geni tourinary system; heart; and sensory organ. Orthologous to human KCNJ15 (potassium inwardly rectifying channel subfamily J member 15). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 95058417 | 95101119 | Mouse | 103 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 62115 | Kcnj16 | potassium inwardly-rectifying channel, subfamily J, member 16 | Predicted to enable inward rectifier potassium channel activity. Predicted to be involved in several processes, including potassium ion import across plasma membrane; regulation of pH; and response to carbon dioxide. Located in basolateral plasma membrane. Is expressed in cerebral cortex; floor plat e; heart; and metanephros. Orthologous to human KCNJ16 (potassium inwardly rectifying channel subfamily J member 16). [provided by Alliance of Genome Resources, Apr 2025] | 11 | 110858859 | 110918794 | Mouse | 121 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |