Enables identical protein binding activity and ubiquitin-modified protein reader activity. Predicted to be involved in several processes, including lysosomal transport; negative regulation of signal transduction; and positive regulation of exosomal secretion. Located in cytoplasm. Is expressed in se
veral structures, including branchial arch; central nervous system; limb bud; sensory organ; and spinal component of peripheral nervous system. Orthologous to human HGS (hepatocyte growth factor-regulated tyrosine kinase substrate). [provided by Alliance of Genome Resources, Jul 2025]
Enables heparan-alpha-glucosaminide N-acetyltransferase activity. Involved in heparan sulfate proteoglycan catabolic process. Is active in lysosomal lumen. Is expressed in central nervous system; eye; and long bone epiphyseal plate. Used to study mucopolysaccharidosis III and mucopolysaccharidosis t
ype IIIC. Human ortholog(s) of this gene implicated in mucopolysaccharidosis type IIIC and retinitis pigmentosa 73. Orthologous to human HGSNAT (heparan-alpha-glucosaminide N-acetyltransferase). [provided by Alliance of Genome Resources, Jul 2025]