Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in tRNA methylation and tRNA wobble uridine modification. Located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 23. Orthologous to human GTPBP3
Predicted to enable several functions, including GTP binding activity; GTPase activity; and preribosome binding activity. Acts upstream of or within maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in cytosol; nucleus; and perinuclear
region of cytoplasm. Predicted to be active in nucleolus. Orthologous to human GTPBP4 (GTP binding protein 4). [provided by Alliance of Genome Resources, Jul 2025]