Fancg Gene Search Result

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2 records found for search term Fancg

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1618385	Fancg	Fanconi anemia, complementation group G	Acts upstream of or within several processes, including DNA damage response; ovarian follicle development; and spermatid development. Predicted to be located in several cellular components, including chromatin; mitochondrion; and nucleolus. Predicted to be part of Fanconi anaemia nuclear complex. Is ... (more) expressed in gut dorsal mesentery and reproductive system. Human ortholog(s) of this gene implicated in Fanconi anemia; Fanconi anemia complementation group G; and pancreatic cancer. Orthologous to human FANCG (FA complementation group G). [provided by Alliance of Genome Resources, Apr 2025]	4	43002337	43010565	Mouse	155	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1614308	Fance	Fanconi anemia, complementation group E	This gene encodes the complementation group E subunit of the multimeric Fanconi anemia (FA) nuclear complex composed of proteins encoded by over ten Fanconi anemia complementation (FANC) group genes: FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG ... (more) '>FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The FA complex is necessary for protection against DNA damage. This gene product is required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2. Defects in the related human gene are a cause of Fanconi anemia, a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. Translation of this protein is initiated at a non-AUG (CUG) start codon, which is inferred from the related human gene and the notion that this protein is functionally indispensable. Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2009]	17	28532504	28545548	Mouse	93	description	gene, protein-coding, REVIEWED [RefSeq]