| 1556908 | Defa6 | defensin, alpha, 6 | Predicted to enable pore-forming activity and protein homodimerization activity. Acts upstream of or within response to bacterium and response to xenobiotic stimulus. Located in extracellular space. Orthologous to human DEFA5 (defensin alpha 5). [provided by Alliance of Genome Resources, Jul 2025] | | | | Mouse | 8 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1612768 | Defa12 | defensin, alpha, 12 | Predicted to enable pore-forming activity and protein homodimerization activity. Predicted to be located in extracellular space; midbody; and secretory granule. [provided by Alliance of Genome Resources, Apr 2025] | | | | Mouse | 7 | old_gene_symbol | gene, protein-coding |
| 1622408 | Defa-rs12 | defensin, alpha, related sequence 12 | Predicted to enable pore-forming activity and protein homodimerization activity. Predicted to be involved in cellular response to lipopolysaccharide; defense response to other organism; and disruption of plasma membrane integrity in another organism. Predicted to be located in midbody and secretory granule. Predicted to be active in extracellular space. Orthologous to human DEFA6 (defensin alpha 6). [provided by Alliance of Genome Resources, Apr 2025] | | | | Mouse | 17 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1620835 | Defa20 | defensin, alpha, 20 | Predicted to enable pore-forming activity and protein homodimerization activity. Involved in killing by host of symbiont cells. Acts upstream of or within antibacterial humoral response. Located in extracellular space. Orthologous to human DEFA4 (defensin alpha 4) and DEFA6 DEFA6 (defensin alpha 6). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 21999274 | 22000253 | Mouse | 29 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1614361 | Defa21 | defensin, alpha, 21 | Predicted to enable protein homodimerization activity. Predicted to be involved in cellular response to lipopolysaccharide; defense response to other organism; and disruption of plasma membrane integrity in another organism. Predicted to be active in extracellular space. Orthologous to human DEFA4 ( defensin alpha 4) and DEFA6 (defensin alpha 6). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 21515561 | 21516533 | Mouse | 74 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2301795 | Defa32 | defensin, alpha, 32 | Predicted to enable pore-forming activity and protein homodimerization activity. Predicted to be located in azurophil granule and extracellular space. Orthologous to human DEFA4 (defensin alpha 4) and DEFA6 (defensin alpha 6). [provided by Alliance of Genome Res ources, Apr 2025] | 8 | 22019046 | 22020028 | Mouse | 14 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2306493 | Defa35 | defensin, alpha, 35 | Predicted to enable pore-forming activity and protein homodimerization activity. Predicted to be involved in cellular response to lipopolysaccharide; defense response to other organism; and disruption of plasma membrane integrity in another organism. Predicted to be located in midbody and secretory granule. Predicted to be active in extracellular space. Orthologous to human DEFA4 (defensin alpha 4) and DEFA6 (defensin alpha 6). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 21555054 | 21556017 | Mouse | 17 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 7179993 | Defa36 | defensin, alpha, 36 | Predicted to enable pore-forming activity and protein homodimerization activity. Predicted to be located in extracellular space; midbody; and secretory granule. Orthologous to human DEFA4 (defensin alpha 4) and DEFA6 (defensin alpha 6). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 21917444 | 21918402 | Mouse | 13 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2295779 | Defa37 | defensin, alpha, 37 | Predicted to enable pore-forming activity and protein homodimerization activity. Predicted to be involved in cellular response to lipopolysaccharide; defense response to other organism; and disruption of plasma membrane integrity in another organism. Predicted to be located in midbody and secretory granule. Predicted to be active in extracellular space. Orthologous to human DEFA4 (defensin alpha 4) and DEFA6 (defensin alpha 6). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 22055402 | 22056366 | Mouse | 8 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1312528 | Defa4 | defensin, alpha, 4 | Enables phospholipid binding activity. Involved in killing of cells of another organism. Acts upstream of or within antibacterial humoral response and disruption of plasma membrane integrity in another organism. Located in extracellular space. Is expressed in duodenum and ileum. Orthologous to sever al human genes including DEFA6 (defensin alpha 6). [provided by Alliance of Genome Resources, Jul 2025] | | | | Mouse | 28 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2295860 | Defa41 | defensin, alpha, 41 | Predicted to enable pore-forming activity and protein homodimerization activity. Predicted to be involved in cellular response to lipopolysaccharide; defense response to other organism; and disruption of plasma membrane integrity in another organism. Predicted to be located in midbody and secretory granule. Predicted to be active in extracellular space. Orthologous to human DEFA4 (defensin alpha 4) and DEFA6 (defensin alpha 6). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 21691620 | 21692462 | Mouse | 21 | description | gene, protein-coding, VALIDATED [RefSeq] |
