Enables DNA binding activity. Acts upstream of or within decidualization; extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of macromolecule metabolic process. Located in cytoplasm and nucleolus. Is expressed in central nervous system and retina. Orthologous t
death effector domain-containing DNA binding protein 2
Predicted to enable DNA binding activity. Predicted to be involved in apoptotic nuclear changes; extrinsic apoptotic signaling pathway via death domain receptors; and positive regulation of extrinsic apoptotic signaling pathway. Predicted to act upstream of or within apoptotic process and regulation
of apoptotic process. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Orthologous to human DEDD2 (death effector domain containing 2). [provided by Alliance of Genome Resources, Apr 2025]