| 62188 | Dcn | decorin | This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate a mature protein product, which is secreted into the extracellular space to regulate collagen fibril assembly. Homozygous knockout mice for this gene exhibit enhanced tumorigenesis in a liver cancer model, and defects in collagen fibrils, leading to weakened skin and tendons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] | 10 | 97315362 | 97354025 | Mouse | 374 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1320133 | Dcun1d1 | defective in cullin neddylation 1 domain containing 1 | Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in positive regulation of protein neddylation; protein neddylation; and regulation of protein ubiquitination. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of ubiquitin ligase complex. Is expressed in several structures, including central nervous system; genitourinary system; liver; lung; and spleen. Orthologous to human DCUN1D1 (defective in cullin neddylation 1 domain containing 1). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 35946254 | 35991626 | Mouse | 116 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1616661 | Dcun1d2 | defective in cullin neddylation 1 domain containing 2 | Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in positive regulation of protein neddylation and protein neddylation. Predicted to be located in cytoplasm and nucleus. Pr edicted to be part of ubiquitin ligase complex. Orthologous to human DCUN1D2 (defective in cullin neddylation 1 domain containing 2). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 13305963 | 13337833 | Mouse | 73 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1318924 | Dcun1d3 | defective in cullin neddylation 1 domain containing 3 | Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; protein neddylation; and regu lation of protein neddylation. Predicted to be located in several cellular components, including cytosol; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be part of ubiquitin ligase complex. Is expressed in central nervous system; reproductive system; and urinary system. Orthologous to human DCUN1D3 (defective in cullin neddylation 1 domain containing 3). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 119452381 | 119495553 | Mouse | 145 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1321316 | Dcun1d4 | defective in cullin neddylation 1 domain containing 4 | Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in positive regulation of protein neddylation and protein neddylation. Predicted to be located in nucleus. Predicted to be part of ubiquitin ligase complex. Is expressed in early conceptus; genitourinary system; nervous system; and neural retina. Orthologous to human DCUN1D4 (defective in cullin neddylation 1 domain containing 4). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 73638353 | 73718137 | Mouse | 114 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1315947 | Dcun1d5 | defective in cullin neddylation 1 domain containing 5 | Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in several processes, including positive regulation of protein neddylation; protein neddylation; and regulation of cell gro wth. Located in nucleus. Is expressed in several structures, including early conceptus; genitourinary system; jaw; nervous system; and thymus primordium. Orthologous to human DCUN1D5 (defective in cullin neddylation 1 domain containing 5). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 7176590 | 7220880 | Mouse | 96 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |