Enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Involved in ubiquinone biosynthetic process. Acts upstream of or within several processes, including chordate embryonic develo
pment; determination of adult lifespan; and mitochondrial ATP synthesis coupled electron transport. Located in mitochondrion. Is extrinsic component of mitochondrial inner membrane. Is expressed in several structures, including alimentary system; ear; heart; respiratory system; and skeleton. Human ortholog(s) of this gene implicated in autosomal recessive distal hereditary motor neuronopathy 9 and primary coenzyme Q10 deficiency 8. Orthologous to human COQ7 (coenzyme Q7, hydroxylase). [provided by Alliance of Genome Resources, Jul 2025]
Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in peptidyl-serine dephosphorylation and positive regulation of ubiquinone biosynthetic process. Located in mitochondrion. Is expressed in several structures, including brain; cardiovascular system; connectiv
e tissue; genitourinary system; and gut. Orthologous to human PPTC7 (protein phosphatase targeting COQ7). [provided by Alliance of Genome Resources, Apr 2025]