Enables histone H3K27me3 reader activity; histone binding activity; and histone deacetylase binding activity. Involved in several processes, including cerebral cortex neuron differentiation; positive regulation of signal transduction by p53 class mediator; and sperm DNA condensation. Located in hete
rochromatin and nucleus. Part of NuRD complex. Is expressed in central nervous system and dorsal root ganglion. Orthologous to human CHD5 (chromodomain helicase DNA binding protein 5). [provided by Alliance of Genome Resources, Jul 2025]
Predicted to enable protein-membrane adaptor activity. Acts upstream of or within several processes, including otic vesicle development; post-translational protein targeting to endoplasmic reticulum membrane; and sensory perception of sound. Predicted to be located in endoplasmic reticulum. Predicte
d to be part of GET complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and skeleton. Orthologous to human GET1 (guided entry of tail-anchored proteins factor 1). [provided by Alliance of Genome Resources, Apr 2025]