Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of DNA-binding transcripti
on factor activity. Located in granular component. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and skeletal muscle tissue. Orthologous to human CARF (calcium responsive transcription factor). [provided by Alliance of Genome Resources, Jul 2025]
Predicted to enable p53 binding activity. Predicted to be involved in several processes, including DNA damage response; regulation of cell growth; and regulation of protein stability. Located in nucleus. Is expressed in brain; olfactory epithelium; and spinal cord. Orthologous to human CDKN2AIP (CDK
Enables opsin binding activity and phosphoprotein binding activity. Acts upstream of or within endocytosis and regulation of protein phosphorylation. Located in photoreceptor outer segment and synapse. Is expressed in retina. Human ortholog(s) of this gene implicated in myopia. Orthologous to human