brain-specific angiogenesis inhibitor 1-associated protein 2
Predicted to enable several functions, including PDZ domain binding activity; proline-rich region binding activity; and scaffold protein binding activity. Involved in actin filament organization; modulation of chemical synaptic transmission; and regulation of cell shape. Acts upstream of or within d
endrite development and regulation of synaptic plasticity. Located in neuron projection. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; attention deficit hyperactivity disorder; and autism spectrum disorder. Orthologous to human BAIAP2 (BAR/IMD domain containing adaptor protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Predicted to enable proline-rich region binding activity. Predicted to be involved in actin crosslink formation; actin filament bundle assembly; and positive regulation of actin filament polymerization. Predicted to be located in plasma membrane. Predicted to be active in cytosol and nucleoplasm. Pr
edicted to colocalize with actin cytoskeleton. Is expressed in several structures, including brain; gut; lung; and nose. Orthologous to human BAIAP2L1 (BAR/IMD domain containing adaptor protein 2 like 1). [provided by Alliance of Genome Resources, Jul 2025]
Enables identical protein binding activity and phospholipid binding activity. Involved in membrane organization. Predicted to be located in cell-cell contact zone and vesicle membrane. Predicted to be part of clathrin complex. Predicted to be active in cytosol and nucleoplasm. Is expressed in brain.