| 1557424 | Arx | aristaless related homeobox | This gene encodes a transcription factor that plays an important role in the development of forebrain. Male mice lacking this gene have smaller brains, olfactory bulbs and testes, and die within half a day after birth. Mice lacking this gene specifically in ganglionic eminence-derived neurons, inclu ding cortical interneurons, develop seizures. Mutations in this gene have been demonstrated to cause mouse phenotypes resembling human X-linked lissencephaly and cognitive disability with epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] | X | 92330113 | 92341963 | Mouse | 277 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1323790 | Uba2 | ubiquitin-like modifier activating enzyme 2 | Enables SUMO activating enzyme activity. Predicted to be involved in positive regulation of protein sumoylation and protein sumoylation. Part of SUMO activating enzyme complex. Is expressed in several structures, including branchial arch; lens; limb; and neural fold. Orthologous to human UBA2 (ubiqu itin like modifier activating enzyme 2). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 33840121 | 33868014 | Mouse | 136 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1617466 | Arxes1 | adipocyte-related X-chromosome expressed sequence 1 | Acts upstream of or within fat cell differentiation. Located in endoplasmic reticulum. Is expressed in axial musculature; eye; incisor; and nervous system. [provided by Alliance of Genome Resources, Jul 2025] | X | 134934116 | 134935695 | Mouse | 22 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1622216 | Arxes2 | adipocyte-related X-chromosome expressed sequence 2 | Acts upstream of or within fat cell differentiation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025] | X | 134894569 | 134896108 | Mouse | 45 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |