Involved in negative regulation of fat cell differentiation. Acts upstream of or within several processes, including glucose homeostasis; negative regulation of organ growth; and negative regulation of signal transduction. Located in actin cytoskeleton. Is expressed in several structures, including
brain; genitourinary system; liver; lung; and spleen. Used to study obesity. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human ANKRD26 (ankyrin repeat domain containing 26). [provided by Alliance of Genome Resources, Jul 2025]