This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 2 and 7. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis thr
Is expressed in several structures, including genitourinary system; heart; lung; skeletal musculature; and skin. Orthologous to human CRYBG1 (crystallin beta-gamma domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Enables D-glucose:proton symporter activity and sucrose:proton symporter activity. Involved in developmental pigmentation; lysosomal lumen pH elevation; and melanin biosynthetic process from tyrosine. Acts upstream of or within sucrose transport. Predicted to be located in melanosome membrane. Predi
cted to be active in membrane. Is expressed in brain; embryo ectoderm; eye; mesenchyme derived from neural crest; and skin. Used to study oculocutaneous albinism. Human ortholog(s) of this gene implicated in oculocutaneous albinism type IV and pigmentation disease. Orthologous to human SLC45A2 (solute carrier family 45 member 2). [provided by Alliance of Genome Resources, Jul 2025]