Enables ADP-ribosylarginine hydrolase activity. Involved in protein modification process. Predicted to be located in extracellular space. Is expressed in cerebral cortex. Orthologous to human ADPRH (ADP-ribosylarginine hydrolase). [provided by Alliance of Genome
Predicted to enable ADP-ribosylarginine hydrolase activity and magnesium ion binding activity. Predicted to be involved in cardiac chamber ballooning and cardiac myofibril assembly. Predicted to be located in sarcomere. Orthologous to human ADPRHL1 (ADP-ribosylh
Enables ADP-ribosylserine hydrolase activity and poly(ADP-ribose) glycohydrolase activity. Involved in negative regulation of necroptotic process and peptidyl-serine ADP-deribosylation. Acts upstream of or within cellular response to superoxide. Located in mitochondrion and nucleus. Human ortholog(s
) of this gene implicated in stress-induced childhood-onset neurodegeneration with variable ataxia and seizures. Orthologous to human ADPRS (ADP-ribosylserine hydrolase). [provided by Alliance of Genome Resources, Jul 2025]