| 1344008 | UBB | ubiquitin B | This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] | 17 | 16380779 | 16382745 | Human | 206 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 616940609 | UBB-AS1 | UBB antisense RNA 1 | | | | | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna |
| 1347287 | UBBP1 | ubiquitin B pseudogene 1 | | 2 | 136329300 | 136330012 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1352261 | UBBP2 | ubiquitin B pseudogene 2 | INTERACTS WITH bisphenol A; silicon dioxide | 1 | 217850259 | 217850731 | Human | 2 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1349521 | UBBP3 | ubiquitin B pseudogene 3 | | 2 | 148863427 | 148863834 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1346838 | UBBP4 | ubiquitin B pseudogene 4 | INTERACTS WITH acrylamide; testosterone; bisphenol A (ortholog) | 17 | 22090750 | 22205151 | Human | 3 | symbol , COSMIC , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 6481543 | UBBP5 | ubiquitin B pseudogene 5 | | 13 | 87219004 | 87219417 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1605374 | UBA6 | ubiquitin like modifier activating enzyme 6 | Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzym e that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM, Mar 2008] | 4 | 67612652 | 67701155 | Human | 100 | description | gene, protein-coding, VALIDATED [RefSeq] |