| 1343497 | TNKS | tankyrase | Enables histone binding activity; pentosyltransferase activity; and zinc ion binding activity. Involved in several processes, including positive regulation of canonical Wnt signaling pathway; post-translational protein modification; and regulation of chromosome organization. Acts upstream of or with in peptidyl-serine phosphorylation and peptidyl-threonine phosphorylation. Located in several cellular components, including chromosome, telomeric region; mitotic spindle pole; and nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 8 | 9555912 | 9782346 | Human | 167 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1312811 | TNKS2 | tankyrase 2 | Enables NAD+ poly-ADP-ribosyltransferase activity; NAD+-protein mono-ADP-ribosyltransferase activity; and enzyme binding activity. Involved in several processes, including positive regulation of canonical Wnt signaling pathway; post-translational protein modification; and regulation of telomere main tenance. Located in nuclear envelope; pericentriolar material; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 10 | 91798426 | 91865475 | Human | 145 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 16566326 | AC021242.3 | novel transcript, antisense to TNKS | | | | | Human | | name | gene, lncrna |
| 1323786 | TNKS1BP1 | tankyrase 1 binding protein 1 | Enables ankyrin repeat binding activity; enzyme binding activity; and protein serine/threonine kinase activator activity. Involved in cellular response to ionizing radiation and double-strand break repair. Located in several cellular components, including adherens junction; heterochromatin; and nucl eus. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 57299642 | 57324952 | Human | 138 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 7241621 | TNKS2-DT | TNKS2 divergent transcript | INTERACTS WITH lipopolysaccharide; okadaic acid; propofol | 10 | 91782839 | 91798291 | Human | 4 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |
| 1350700 | FNBP1 | formin binding protein 1 | The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human. [provided by RefSeq, Jul 2008] | 9 | 129887187 | 130053879 | Human | 142 | description | gene, protein-coding, REVIEWED [RefSeq] |