Tia1 Gene Search Result

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4 records found for search term Tia1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1313955	TIA1	TIA1 cytotoxic granule associated RNA binding protein	The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers ... (more) and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017]	2	70209444	70248793	Human	266	symbol , old_gene_name , COSMIC , name , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1345557	TIAL1	TIA1 cytotoxic granule associated RNA binding protein like 1	The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptos ... (more) is. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq, Jul 2008]	10	119573465	119596964	Human	140	old_gene_name , name	gene, protein-coding, REVIEWED [RefSeq]
16565465	TIAL1P1	TIAL1 pseudogene		6	51385301	51385826	Human		old_gene_name	gene, pseudo, INFERRED [RefSeq]
1605699	FASTK	Fas activated serine/threonine kinase	The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-pr ... (more) omoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]	7	151076624	151080809	Human	122	description	gene, protein-coding, REVIEWED [RefSeq]