Spt1 Gene Search Result

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3 records found for search term Spt1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1315336	SPTLC1	serine palmitoyltransferase long chain base subunit 1	This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and i ... (more) s the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013]	9	92031147	92115413	Human	329	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1320698	SUPT16H	SPT16 homolog, facilitates chromatin remodeling subunit	Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT ... (more) (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]	14	21351476	21384019	Human	187	old_gene_name , name , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
2289750	SUPT16HP1	SPT16 homolog, facilitates chromatin remodeling subunit pseudogene 1		12	16398875	16402509	Human		name	gene, pseudo, INFERRED [RefSeq]