Spry4 Gene Search Result

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Genes search result for Homo sapiens
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3 records found for search term Spry4

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1313286	SPRY4	sprouty RTK signaling antagonist 4	This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene ... (more) has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014]	5	142310430	142325021	Human	276	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
12903136	SPRY4-AS1	SPRY4 antisense RNA 1	INTERACTS WITH mono(2-ethyl-5-hydroxyhexyl) phthalate; mono(2-ethyl-5-oxohexyl) phthalate; mono(2-ethylhexyl) phthalate	5	142325293	142464054	Human	9	symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
5135340	SPRY4-IT1	SPRY4 intronic transcript 1	This gene produces a non-coding RNA that is upregulated in several different tumors, including melanoma and breast and prostate cancer cells. This transcript may mediate cell growth, proliferation, and apoptosis. It regulates levels of lipin 2, and therefore may be involved in lipid biosynthesis. Th ... (more) e primary transcript is cleaved to release a mature product that localizes to the cytoplasm (PMID:25344859). The full length structure of the primary and cleaved transcripts is unclear, and it is possible that the primary transcript is a splice variant of SPRY4 (sprouty RTK signaling antagonist 4). [provided by RefSeq, Feb 2016]	5	142317620	142318322	Human	2	symbol , GTEx , COSMIC , name , description , Human Proteome Map	gene, ncrna, REVIEWED [RefSeq]