Snx15 Gene Search Result

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2 records found for search term Snx15

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1314058	SNX15	sorting nexin 15	This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth f ... (more) actor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. [provided by RefSeq, Dec 2010]	11	65027439	65040572	Human	72	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
7370113	ARL2-SNX15	ARL2-SNX15 readthrough (NMD candidate)	This locus represents naturally occurring read-through transcription between the neighboring ADP-ribosylation factor-like 2 (ARL2) and sorting nexin 15 (SNX15) genes on chromosome 11. The read-through transcript is a candidate for nonsense-mediated mRNA decay (N ... (more) MD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Dec 2010]	11	65014160	65040572	Human	8	symbol , COSMIC , name , description , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]