| 1343667 | SDCBP | syndecan binding protein | The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also aff ect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Jan 2017] | 8 | 58553261 | 58582858 | Human | 225 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1317056 | SDCBP2 | syndecan binding protein 2 | The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protei n binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031. [provided by RefSeq, Sep 2011] | 20 | 1309909 | 1329139 | Human | 131 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 7175589 | SDCBPP1 | syndecan binding protein pseudogene 1 | | 10 | 6292906 | 6294740 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7175684 | SDCBPP2 | syndecan binding protein pseudogene 2 | | 8 | 69942809 | 69944286 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7175935 | SDCBPP3 | syndecan binding protein pseudogene 3 | | X | 40890519 | 40891594 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 10399286 | SDCBP2P1 | syndecan binding protein 2 pseudogene 1 | INTERACTS WITH cadmium dichloride | 6 | 73322837 | 73323450 | Human | 1 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 6893194 | SDCBP2-AS1 | SDCBP2 antisense RNA 1 | INTERACTS WITH aflatoxin B1; cadmium dichloride; DDE | 20 | 1325343 | 1378735 | Human | 14 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 5133080 | FKBP1A-SDCBP2 | FKBP1A-SDCBP2 readthrough (NMD candidate) | This locus represents naturally occurring read-through transcription between the neighboring FK506 binding protein 1A, 12kDa and syndecan binding protein (syntenin) 2 genes on chromosome 20. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Dec 2010] | 20 | 1309909 | 1393172 | Human | 2 | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |