Rnh1 Gene Search Result

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3 records found for search term Rnh1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
735371	RNH1	ribonuclease/angiogenin inhibitor 1	Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhib ... (more) itor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010]	11	494515	507242	Human	156	symbol , COSMIC , Human Proteome Map	gene, protein-coding, VALIDATED [RefSeq]
1319116	RNASEH1	ribonuclease H1	This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The productio ... (more) n of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17. [provided by RefSeq, Jul 2017]	2	3531813	3558333	Human	167	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1604714	RNASEH1P1	ribonuclease H1 pseudogene 1		17	20901955	20902777	Human		old_gene_symbol	gene, pseudo, INFERRED [RefSeq]