Ptpru Gene Search Result

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2 records found for search term Ptpru

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1353626	PTPRU	protein tyrosine phosphatase receptor type U	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellul ... (more) ar region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported. [provided by RefSeq, Aug 2010]	1	29236522	29326800	Human	146	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
16553061	AL671862.1	protein tyrosine phosphatase, receptor type, U (PTPRU) pseudogene					Human		name	gene, unprocessed_pseudogene