Psmd8 Gene Search Result

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4 records found for search term Psmd8

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1320403	PSMD8	proteasome 26S subunit, non-ATPase 8	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. T ... (more) he 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]	19	38374571	38383824	Human	134	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
16563872	AP000894.1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (PSMD8) pseudogene					Human		name	gene, processed_pseudogene
1603053	NOB1	NIN1 (RPN12) binding protein 1 homolog	In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and bindin ... (more) g of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010]	16	69741871	69754926	Human	101	old_gene_name , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
5684151	PSMD8P1	proteasome 26S subunit, non-ATPase, 8 pseudogene 1		1	154414272	154415222	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]