| 1344150 | PHF1 | PHD finger protein 1 | This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-r ay sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] | 6 | 33410412 | 33416439 | Human | 121 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1313192 | PHF10 | PHD finger protein 10 | This gene contains a predicted ORF that encodes a protein with two zinc finger domains. The function of the encoded protein is not known. Sequence analysis suggests that multiple alternatively spliced transcript variants are derived from this gene but the full-length nature of only two of them is kn own. These two splice variants encode different isoforms. A pseudogene for this gene is located on Xq28. [provided by RefSeq, Jul 2008] | 6 | 169703902 | 169724500 | Human | 105 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1321995 | PHF11 | PHD finger protein 11 | This gene encodes a protein containing a PHD (plant homeodomain) type zinc finger. This gene has been identified in some studies as a candidate gene for asthma. Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] | 13 | 49495953 | 49528976 | Human | 109 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1313935 | PHF12 | PHD finger protein 12 | Enables phosphatidylinositol binding activity and transcription corepressor activity. Involved in negative regulation of DNA-templated transcription. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of Sin3-type complex and transcript ion repressor complex. [provided by Alliance of Genome Resources, Jul 2025] | 17 | 28905250 | 28951518 | Human | 76 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1317748 | PHF13 | PHD finger protein 13 | Enables chromatin binding activity; chromatin-protein adaptor activity; and methylated histone binding activity. Involved in mitotic chromosome condensation and regulation of DNA repair. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025] | 1 | 6613731 | 6624030 | Human | 79 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1349780 | PHF14 | PHD finger protein 14 | Enables histone binding activity. Predicted to be involved in several processes, including germinal center B cell differentiation; lung development; and negative regulation of mesenchymal cell proliferation involved in lung development. Located in chromatin; cytoplasm; and nucleus. [provided by Alli ance of Genome Resources, Jul 2025] | 7 | 10973872 | 11169618 | Human | 107 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1321268 | PHF19 | PHD finger protein 19 | Enables methylated histone binding activity. Involved in negative regulation of gene expression, epigenetic. Located in ESC/E(Z) complex. [provided by Alliance of Genome Resources, Apr 2025] | 9 | 120855651 | 120904128 | Human | 153 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1354183 | PHF10P1 | PHD finger protein 10 pseudogene 1 | | X | 155291939 | 155293441 | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 38644258 | PHF10P2 | PHF10 pseudogene 2 | | 22 | 25349544 | 25350609 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 38616362 | SETDB2-PHF11 | SETDB2-PHF11 readthrough | This gene represents naturally-occurring readthrough transcription between the upstream SETDB2 (SET domain bifurcated 2) gene to the downstream PHF11 (PHD finger protein 11) gene. Readthrough transcripts may encode fusion proteins with similarity to proteins enc oded by each of the individual genes or may encode candidates for nonsense-mediated decay (NMD). [provided by RefSeq, Mar 2016] | 13 | 49444274 | 49528976 | Human | | symbol , GTEx , old_gene_name , COSMIC , name , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1321844 | CXXC1 | CXXC finger protein 1 | This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development. [provided by RefSeq, Sep 201 5] | 18 | 50282347 | 50287692 | Human | 104 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1315809 | JADE1 | jade family PHD finger 1 | Enables transcription coactivator activity. Contributes to histone acetyltransferase activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; regulation of cell growth; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle. Located in several cellular components, including cytosol; microtubule organizing center; and nuclear speck. Part of histone acetyltransferase complex. [provided by Alliance of Genome Resources, Jul 2025] | 4 | 128809700 | 128875224 | Human | 181 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1319333 | JADE2 | jade family PHD finger 2 | Enables histone H4K12 acetyltransferase activity; histone H4K5 acetyltransferase activity; and histone H4K8 acetyltransferase activity. Contributes to histone H3K14 acetyltransferase activity. Involved in regulation of DNA biosynthetic process; regulation of DNA replication; and regulation of cell c ycle. Located in nucleoplasm. Part of histone acetyltransferase complex. [provided by Alliance of Genome Resources, Jul 2025] | 5 | 134524009 | 134583227 | Human | 128 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1344107 | JADE3 | jade family PHD finger 3 | This gene encodes a member of a family of large proteins containing PHD (plant homeo domain)-type zinc fingers. The encoded protein may be associated in a nuclear complex that functions in histone H4 acetylation. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013] | X | 46912301 | 47061242 | Human | 64 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 16564145 | AC024267.4 | novel transcript, antisense to PHF12 | | 17 | 28926275 | 28944749 | Human | | name | gene, ncrna, VALIDATED [RefSeq] |
| 16564152 | AC024267.5 | novel transcript, antisense to PHF12 | | | | | Human | | name | gene, lncrna |
| 16555041 | AL022324.2 | PHD finger protein 10 (PHF10) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 1321179 | SETDB2 | SET domain bifurcated histone lysine methyltransferase 2 | This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] | 13 | 49444274 | 49495003 | Human | 80 | description | gene, protein-coding, REVIEWED [RefSeq] |
