Peg3 Gene Search Result

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5 records found for search term Peg3

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1322359	PEG3	paternally expressed 3	In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exo ... (more) ns unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009]	19	56810082	56840726	Human	124	symbol , COSMIC , description , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
2301272	PEG3-AS1	PEG3 antisense RNA 1	This gene is located in the paternally expressed gene 3 (PEG3) imprinted region on chromosome 19. The corresponding transcript in mouse is imprinted and regulates expression of the mouse Peg3 gene. [provided by RefSeq, Sep 2 ... (more) 016]	19	56812480	56813793	Human	8	symbol , GTEx , COSMIC , name , description , Human Proteome Map , old_gene_symbol	gene, ncrna, VALIDATED [RefSeq]
1319059	MELK	maternal embryonic leucine zipper kinase	Enables calcium ion binding activity; non-membrane spanning protein tyrosine kinase activity; and protein serine/threonine kinase activity. Involved in apoptotic process; cell population proliferation; and protein autophosphorylation. Located in cell cortex and plasma membrane. [provided by Alliance ... (more) of Genome Resources, Jul 2025]	9	36572895	36677682	Human	195	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]
1349311	ZIM2	zinc finger imprinted 2	In human, ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5' exons and have a common promoter, and both genes are paternally expressed. Alternative splicing events connect the shared exons either with the remaining 4 exons unique to ZIM2, ... (more) or with the remaining 2 exons unique to PEG3. This is in contrast to mouse and cow, where ZIM2 and PEG3 genes do not share exons in common, and the imprinting status of ZIM2 is also not conserved amongst mammals. Additional 5' alternatively spliced transcripts encoding the same protein have been found for the human ZIM2 gene. [provided by RefSeq, Oct 2010]	19	56774547	56840726	Human	23	description	gene, protein-coding, REVIEWED [RefSeq]
9586533	ZIM2-AS1	ZIM2 antisense RNA 1	INTERACTS WITH aristolochic acid A	19	56765322	56799646	Human	1	ensembl_full_name	gene, ncrna, VALIDATED [RefSeq]