Mkrn1 Gene Search Result

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4 records found for search term Mkrn1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1347564	MKRN1	makorin ring finger protein 1	This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thoug ... (more) ht to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21, a cell cycle regulator, and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1, 3, 9, 12 and 20, and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]	7	140453033	140479569	Human	81	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
16556058	AC009969.1	makorin, ring finger protein 1 (MKRN1) pseudogene					Human		name	gene, processed_pseudogene
16556743	AL512353.3	makorin, ring finger protein, 1 (MKRN1) pseudogene					Human		name	gene, processed_pseudogene
38660642	MKRN10P	makorin ring finger protein 10, pseudogene		9	96725821	96727467	Human		symbol , GTEx , COSMIC , Human Proteome Map	gene, pseudo, PROVISIONAL [RefSeq]